个人简介：贾瑜倩，女，中共党员，博士，校聘副教授。

2018年6月本科毕业于河北农业大学动物药学专业，2024年6月博士毕业于扬州大学兽医学院。同年11月作为引进人才入职河北农业大学动物医学院。主要从事抗耐药菌感染新策略的研究，包括新型抗菌增效剂及基因转移抑制剂的发现，耐药新靶点的探究等。目前在Journal of Pineal Research、Pharmacological Research等杂志以第一作者发表SCI论文6篇，主持河北农业大学引进人才科研专项1项，参与国家自然科学基金面上项目、江苏省农业自主创新项目、江苏省重点研究计划等科研项目。

电子邮箱：jiayq2019@163.com

通讯地址：河北省保定市莲池区乐凯南大街河北农业大学西校区

研究方向：细菌耐药性防控新策略研究

代表性论文：

1. Yuqian Jia, Bingqing Yang, Jingru Shi, Dan Fang, Zhiqiang Wang, Yuan Liu. Melatonin prevents conjugative transfer of plasmid-mediated antibiotic resistance genes by disrupting proton motive force. Pharmacological Research. 2021, 175: 105978. IF=9.3.

2. Yuqian Jia, Bingqing Yang, et al. Melatonin protects intestinal against the inflammation and flora dysbiosis reshapes gut microbiota and remits the inflammation induced by megadose colistin. Journal of Pineal Research. 2024, 76(5): e12989. IF=8.3. (中科院一区)

3. Yuqian Jia, Zhiqiang Wang, Dan Fang, Bingqing Yang, Ruichao Li, Yuan Liu. Acetaminophen promotes horizontal transfer of plasmid-borne multiple antibiotic resistance genes. Science of the Total Environment. 2021, 8(782): 509-522. IF=9.736. (中科院一区TOP)

4. Yuan Liu^#, Yuqian Jia^#, Kangni Yang, Ziwen Tong, Jingru Shi, Ruichao Li, Xia Xiao, Wenkai Ren, Rüdiger Hardeland, Russel J. Reiter, Zhiqiang Wang. Melatonin overcomes MCR-mediated colistin resistance in Gram-negative pathogens. Theranostics. 2020, 10 (23): 10697-10711. IF=11.556. (中科院一区TOP)

5. Yuqian Jia, Zeyu Wang, Shuyao Zhu, Zhiqiang Wang, Yuan Liu. Disinfectants facilitate the transformation of exogenous antibiotic resistance genes via multiple pathways. Ecotoxicology and Environmental Safety. 2023, 253(9): 114678. IF=6.8. (中科院二区TOP)

6. Yuqian Jia, Zhiwan Zheng, Bingqing Yang, et al. A broad-spectrum horizontal transfer inhibitor blocks the transmission of antibiotic resistance. Transboundary and Emerging Diseases. 2024. 2024:13. IF=3.5. (中科院二区TOP)

7. Yuan Liu, Yuqian Jia, Kangni Yang, Ruichao Li, Xia Xiao, Kui Zhu, and Zhiqiang Wang. Metformin Restores Tetracyclines Susceptibility against Multidrug Resistant Bacteria. Advanced Science. 2020, 7(12):1902227. IF=15.1. (中科院一区TOP)

8. Yuan Liu, Yuqian Jia, Kangni Yang, Ruichao Li, Xia Xiao, Zhiqiang Wang. Anti-HIV agent azidothymidine decreases Tet(X)-mediated bacterial resistance to tigecycline in Escherichia coli. Communications Biology. 2020, 3(1):162. IF=5.9.

9. Yuan Liu, Kangni Yang, Yuqian Jia, Ruichao Li, Xia Xiao, Zhiqiang Wang. Gut microbiome alterations in high-fat-diet-fed mice are associated with antibiotic tolerance. Nature Microbiology. 2021, 6(7):874-884. IF=30.964. (中科院一区TOP)

参与发明专利

1.二甲双胍和多西环素的组合物及其在制备细菌感染性疾病的药物中的应用

(公开号: CN109432107A)。

2.褪黑素的用途(公开号: CN109999027A)。

3.叠氮胸苷的新用途(公开号: CN110368396A)。

4.双硫仑在细菌感染疾病中的潜在应用(公开号: CN110974814A)。

5.黄酮类化合物在制备抑制耐药质粒接合转移的药物中的应用(公开号: CN116492330A)。