个人简介

朱伟峰，男，博士，博士后，副教授，硕士生导师，学校引进人才。主讲《兽医内科学》等本科生课程。主要研究方向包括动物疫病防控与净化、抗菌药替代产品研究、病原细菌的感染与免疫机制。近年来以猪链球菌、猪丹毒丝菌、巴氏杆菌、支气管败血波氏菌等畜禽常见病原菌为研究对象开展研究，发现了病原菌的群体特征和流行特征，建立了新的诊断方法，发现了新的致病和免疫机制，研制了新的疫苗和防控药物，有效提升了养殖业的效益。近五年来主持或参加省级以上项目10项，参编专著2部，发表高水平学术论文30余篇（第一或通讯作者SCI论文11篇），申报发明专利8件，制定地方标准1项，参与研制新兽药6项。

主讲课程：《兽医内科学》

研究领域：动物疫病防控与净化、抗菌药替代产品研究、病原细菌的感染与免疫机制

电子邮箱：zhuweifeng8@126.com

通讯地址：河北省保定市竞秀区乐凯南大街2596号农大西校区动物医学院

一、专著

1. 朱伟峰，细菌病部分，兔病图鉴，王芳、范志宇、薛家宾主编，中国农业科学技术出版社，ISBN 978-7-5116-4083-3，2019

2. 朱伟峰，细菌病用药，兔场兽药规范使用手册，薛家宾、姚文生主编，中国农业出版社，ISBN978-7-109-23984-5, 2018

    

二、代表性基础研究论文

1. Zhu Weifeng, Zhang Qiang, Li Jingtao, Wei Yanmin, Cai Chengzhi, Liu Liang, Xu Zhongmin, Jin Meilin. Glyceraldehyde-3-phosphate dehydrogenase acts as an adhesin in Erysipelothrix rhusiopathiae adherence to porcine endothelial cells and as a receptor in recruitment of host plasminogen and fibronectin. Veterinary Research. 2017, 48(1): 16-22.

2. Zhu Weifeng#, Wei Houjun#, Chen Lu, Qiu Rulong, Fan Zhiyu, Hu Bo, Chen Mengmeng, Wang Fang. Characterization of host plasminogen exploitation of Pasteurella multocida, Microbial Pathogenesis, 2019, 129: 74-77.

3. Zhu, Weifeng, Cai, Chengzhi, Huang, Jingjing, Liu, Liang, Xu, Zhongmin, Sun, Xiaomei, Jin, Meilin. Characterization of pathogenic roles of two Erysipelothrix rhusiopathiae surface proteins. Microbial Pathogenesis. 2018, 114: 166-168.

4. Zhu Weifeng, Cai Chengzhi, Wang Ya, Li Jingtao, Wu Chao, Kang Chao, Sun Xiaomei, Jin Meilin. Characterization of roles of SpaA in Erysipelothrix rhusiopathiae adhesion to porcine endothelial cells. Microbial Pathogenesis. 2017, 113: 176-180.

5. Zhu Weifeng, Wang Ya, Cai Chengzhi, Li Jingtao, Wu Chao, Jin Meilin. Erysipelothrix rhusiopathiae recruits host plasminogen via the major protective antigen SpaA. FEMS Microbiology Letters, 2017. 364(5): fnx036.

6. Zhu Weifeng; Cai Chengzhi; Li Jingtao; Zhang Qiang; Huang Jingjing; Jin, Meilin*; Characterization of protective antigen CbpB as an adhesin and a plasminogen-binding protein of Erysipelothrix rhusiopathiae, Research in Veterinary Science, 2019, 124: 352-356.

7. 朱伟峰，陈露，王芳，胡波，陈萌萌. 巴氏杆菌糖酵解酶的黏附作用研究.微生物学报.2021, 61(10): 1-16

三、代表性应用研究论文

1. Zhu Weifeng, Wu Chao, Kang Chao, Cai Chengzhi, Wang Ya, Li Jingtao, Zhang Qiang, Sun Xiaomei, Jin Meilin. Evaluation of the protective efficacy of four newly identified surface proteins of Erysipelothrix rhusiopathiae. Vaccine. 2018, 36(52), 8079-8083.

2. Zhu Weifeng, Fan Zhiyu, Qiu Rulong, Chen Lu，Wei Houjun, Hu Bo Chen Mebngmeng, Wang Fang. Characterization of Pasteurella multocida isolates from rabbits in China. Veterianry Microbiology, 2020,244, 108649.

3. Zhu Weifeng, Wu Chao, Kang Chao, Cai Chengzhi, Jin Meilin. Development of a duplex PCR for rapid detection and differentiation of Erysipelothrix rhusiopathiae vaccine strains and wild type strains. Veterinary Microbiology, 2017, 199: 108-110.

4. Zhu Weifeng, Wu Chao, Sun Xiaomei, Zhang Anding, Zhu Jian, Hua Yafeng, Chen Huanchun, Jin Meilin. Characterization of Streptococcus suis serotype 2 isolates from China. Veterinary Microbiology, 2013, 166(3-4): 527-534.

5. Zhu Weifeng, Li Jingtao,Wang Ya, Kang Chao, Jin Meilin, Chen Huanchun. Evaluation and improvement of a single nucleotide polymorphism-based PCR assay for rapid differentiation of live attenuated vaccine strains from field isolates of Erysipelothrix rhusiopathiae. Journal of Veterianry Diagnostic Investigation, 2016, 28(6): 714-717.

6. 朱伟峰, 谭凯, 王芳, 程序, 仇汝龙，范志宇, 陈露. 支气管败血波氏菌BcfA重组蛋白的截短表达及其免疫活性分析.江苏农业学报.2021， 37(03): 699-703

7. 朱伟峰，陈露，王芳，胡波， 阮智杨， 王高杰. 巴氏杆菌糖酵解酶的免疫保护效应研究.中国畜牧兽医.2021， 48(06): 2188-2195.

8. 朱伟峰，范志宇，胡波，魏后军，王芳，陈露. 嵌合了巴氏杆菌抗原表位的兔出血症病毒VP60重组蛋白的构建.中国动物传染病学报.

   (DOI:10.19958/j.cnki.cn31-2031/s.20210611.004)

9. 朱伟峰，陈露，谭凯，王高杰，阮志扬. 猪丹毒丝菌GAPDH线性B细胞表位预测与鉴定江苏农业科学. 2021, 49(22): 171-174

10. 朱伟峰，陈露，谭凯，王高杰，阮志扬.巴氏杆菌GAPDH线性B细胞表位预测与鉴定. 养殖与饲料. 2021, 20(11): 16-19

四、授权专利

（1）金梅林，朱伟峰，吴超，康超，蔡承志，王雅，李敬涛，张强. 一种中国猪丹毒弱毒疫苗株的特异性序列及应用. 2018, ZL201610407489.3

(2) 金梅林，李敬涛，王雅，康超，孙小美，朱伟峰，吴超. 一种红斑丹毒丝菌亚单位疫苗及制备方法及应用.2019， ZL201510159179.X

五、地方标准

（1）金梅林，吴超，朱伟峰，孙小美，范俊青，康超，徐高原.猪丹毒（红斑丹毒丝菌）PCR鉴别诊断技术规程，湖北省地方标准. 2020，DB42/T 1594-2020

六、新兽药

1. 猪链球菌病、副猪嗜血杆菌病二联亚单位疫苗. 获得一类新兽药证书，（2019）新兽药证字9号，2019.03

2. 猪链球菌病活疫苗（SS2-RD株）。获得三类新兽药证书，（2019）新兽药证字10号，2019.03

3. 猪丹毒基因工程亚单位疫苗，获得临床试验批件.2020,2020020

4. 兔出血症病毒杆状病毒载体、多杀性巴氏杆菌病（BAC-VP60株+C51-17株）二联灭活疫苗，获得临床试验批件.2017,2017087

5. 兔病毒性出血症、兔巴氏杆菌病二联亚单位疫苗研究，临床前研究

6. 兔病毒性出血症二价疫苗研究，临床前研究